hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-03342975/chunk_1/iprscan-20080502-03342975.nocrc
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Query sequence: KIAA1463
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
PF00501.18.fs AMP-binding enzyme                          163.5    4.9e-46   3
PF00501.18.ls AMP-binding enzyme                          148.8    1.3e-41   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
PF00501.18.fs   3/3     612  1085 ..     1   377 []   146.8  5.4e-41
PF00501.18.ls   1/1     612  1085 ..     1   377 []   148.8  1.3e-41

Alignments of top-scoring domains:
PF00501.18.fs: domain 3 of 3, from 612 to 1085: score 146.8, E = 5.4e-41
                   *->TYrELderanrlAaaLr.alGvgpGdrVaillpnspelvvailAvlk
                      +  +L+ ra+r+A++L ++  + +Gd V +l p ++el++a++++l 
    KIAA1463   612    SCLQLHKRAERIASVLGdKGHLNAGDNVVLLYPPGIELIAAFYGCLY 658  

                   aGaayvPldpsypa......erlayiledsgakvlltddalla.l.....
                   aG+++v++ p + ++ + +   ++ i++ s+a+++lt+  l + l + ++
    KIAA1463   659 AGCIPVTVRPPHAQnltatlPTVRMIVDVSKAACILTSQTLMRlLrsrea 708  

                   .....................s.e.p.ppvdpddlAyiiYTSGTTGkPKG
                   ++++++++ ++  ++++ + +  +++  p++p+ lAy+ ++  TTG+  G
    KIAA1463   709 aaavdvktwptiidtddlprkRlPqLyKPPTPEMLAYLDFSVSTTGMLTG 758  

                   VmltHrnlvnlvaala.rf.l.pddaervllllppllhfdgsvweifgpL
                   V ++H ++ +l++a+  +++l      r ++   ++++  g+ ++ ++++
    KIAA1463   759 VKMSHSAVNALCRAIKlQCeLySS---RQIAICLDPYCGLGFALWCLCSV 805  

                   laGatlvlvpkfdryrdpealldliekykvTvlflvPtllrlllkape..
                   ++G++ vl+p+ ++  +  ++l ++++yk+  +f+  ++++l+ k   ++
    KIAA1463   806 YSGHQSVLIPPMELENNLFLWLSTVNQYKIRDTFCSYSVMELCTKGLGnq 855  

                   ........edlssLrlvlsgGealpp.elarrlrerfgs...........
                    +  ++++ +ls +r++++++e  p+ +l + + ++f++ + +++  +++
    KIAA1463   856 vevlktrgINLSCVRTCVVVAEERPRvALQQSFSKLFKDiglspravstt 905  

                   ......ggvrlvngYGpTEttvvatanppg.p..............pgsi
                    +++ ++ + l  + Gp  ttv +    + +++ +  +++ + +   +  
    KIAA1463   906 fgsrvnVAICLQGTSGPDPTTVYVDLKSLRhDrvrlvergapqsllLSES 955  

                   GrPlpgvevyvlDeeg.qpvppGevGELyirGwpgvarGYlnrPelTaer
                   G+ lpgv+v+++++e++ pv++   GE+++ + p+ a GY+   +   e+
    KIAA1463   956 GKILPGVKVVIVNPETkGPVGDSHLGEIWVNS-PHTASGYYTIYD--SET 1002 

                   Fvadgwgp........GeRmYrTGDlgrwdpD..........GyleilGR
                     ad +  + + ++  ++ + rTG lg ++  + +  +++++  l+++G 
    KIAA1463  1003 LQADHFNTrlsfgdaaQTLWARTGYLGFVRRTeltaatgerhDALYVVGA 1052 

                   kDdqvKirGerIepgEiEavLl.ahPgVaeAaV<-*
                   +D+   +rG r  p +iE+ +++ h  +ae+aV   
    KIAA1463  1053 LDETLELRGLRYHPIDIETSVSrIHRSIAECAV    1085 

PF00501.18.ls: domain 1 of 1, from 612 to 1085: score 148.8, E = 1.3e-41
                   *->TYrELderanrlAaaLr.alGvgpGdrVaillpnspelvvailAvlk
                      +  +L+ ra+r+A++L ++  + +Gd V +l p ++el++a++++l 
    KIAA1463   612    SCLQLHKRAERIASVLGdKGHLNAGDNVVLLYPPGIELIAAFYGCLY 658  

                   aGaayvPldpsypa......erlayiledsgakvlltddalla.l.....
                   aG+++v++ p + ++ + +   ++ i++ s+a+++lt+  l + l + ++
    KIAA1463   659 AGCIPVTVRPPHAQnltatlPTVRMIVDVSKAACILTSQTLMRlLrsrea 708  

                   .....................s.e.p.ppvdpddlAyiiYTSGTTGkPKG
                   ++++++++ ++  ++++ + +  +++  p++p+ lAy+ ++  TTG+  G
    KIAA1463   709 aaavdvktwptiidtddlprkRlPqLyKPPTPEMLAYLDFSVSTTGMLTG 758  

                   VmltHrnlvnlvaala.rf.l.pddaervllllppllhfdgsvweifgpL
                   V ++H ++ +l++a+  +++l      r ++   ++++  g+ ++ ++++
    KIAA1463   759 VKMSHSAVNALCRAIKlQCeLySS---RQIAICLDPYCGLGFALWCLCSV 805  

                   laGatlvlvpkfdryrdpealldliekykvTvlflvPtllrlllkape..
                   ++G++ vl+p+ ++  +  ++l ++++yk+  +f+  ++++l+ k   ++
    KIAA1463   806 YSGHQSVLIPPMELENNLFLWLSTVNQYKIRDTFCSYSVMELCTKGLGnq 855  

                   ........edlssLrlvlsgGealpp.elarrlrerfgs...........
                    +  ++++ +ls +r++++++e  p+ +l + + ++f++ + +++  +++
    KIAA1463   856 vevlktrgINLSCVRTCVVVAEERPRvALQQSFSKLFKDiglspravstt 905  

                   ......ggvrlvngYGpTEttvvatanppg.p..............pgsi
                    +++ ++ + l  + Gp  ttv +    + +++ +  +++ + +   +  
    KIAA1463   906 fgsrvnVAICLQGTSGPDPTTVYVDLKSLRhDrvrlvergapqsllLSES 955  

                   GrPlpgvevyvlDeeg.qpvppGevGELyirGwpgvarGYlnrPelTaer
                   G+ lpgv+v+++++e++ pv++   GE+++ + p+ a GY+   +   e+
    KIAA1463   956 GKILPGVKVVIVNPETkGPVGDSHLGEIWVNS-PHTASGYYTIYD--SET 1002 

                   Fvadgwgp........GeRmYrTGDlgrwdpD..........GyleilGR
                     ad +  + + ++  ++ + rTG lg ++  + +  +++++  l+++G 
    KIAA1463  1003 LQADHFNTrlsfgdaaQTLWARTGYLGFVRRTeltaatgerhDALYVVGA 1052 

                   kDdqvKirGerIepgEiEavLl.ahPgVaeAaV<-*
                   +D+   +rG r  p +iE+ +++ h  +ae+aV   
    KIAA1463  1053 LDETLELRGLRYHPIDIETSVSrIHRSIAECAV    1085 

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